About Caphosol®

What is Caphosol®?

Caphosol® is an electrolyte solution for the prevention and treatment of oral mucositis.1 Caphosol® is indicated for dryness of the mouth and oropharynx regardless of the cause or whether the conditions are temporary or permanent.1 Caphosol® can also be used as an adjunct to standard oral care in the prevention and treatment of the mucositis that may be caused by radiation or high dose chemotherapy.1

Caphosol® is designed to moisten, lubricate and clean the oral cavity including the mucosa of mouth, tongue and oropharynx.1Additionally, Caphosol® helps maintain the integrity of the oral cavity.2


Who can use Caphosol®?

Caphosol® can be used by patients receiving radiation or high-dose chemotherapy to prevent and treat oral mucositis. Caphosol® can also be used by patients suffering from dryness of the mouth and oropharynx regardless of the cause or whether the conditions are temporary or permanent.1


How can Caphosol® help patients with oral mucositis?

Caphosol® contains high concentrations of calcium and phosphate ions. Calcium and phosphate are important in maintaining a healthy oral cavity. Caphosol® can help patients with oral mucositis by:

  • Facilitating chewing and speaking
  • Loosening tough mucus
  • Preventing mucous membranes sticking together
  • Relieving dryness of the oral mucosa is associated with amelioration of pain

The safety and efficacy of Caphosol® in treating oral mucositis has been clinically demonstrated.2 Caphosol® was shown to:

  • Reduce the duration of oral mucosisits2
  • Reduce the duration of pain associated with oral mucositis2
  • Reduce the requirement for opioid analgesics2

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Caphosol® has also been shown to have a clinically significant impact on the occurrence and severity of oral mucosits in an open-label observational registry.3

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Through preventing and treating oral mucositis associated with cancer therapies, the risk of interrupting cancer treatment is reduced.


References

Note: All the references are available on request to EUSA Pharma

1. Caphosol®Product information. EUSA Pharma (Europe) Limited, Nov 2008
2. Papas AS et al. Bone Marrow Transplant 2003;31:705–712
3. Haas M et al. 50th ASTRO congress 2008; abstract 2530

This website contains information about Oral Mucositis and the use of Caphosol for the prevention and treatment of Oral Mucositis
Caphosol is a class I medical device, marked CE

©EUSA Pharma (Europe) Ltd. May 2009. All rights reserved. www.eusapharma.com
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